Important Safety Information: Risk of Thyroid C-Cell Tumors 

In animal studies, Semaglutide has been shown to cause thyroid tumors, including thyroid cancer, in mice and rats. It is currently unknown whether Semaglutide poses the same risk in humans. If you notice symptoms such as a lump or swelling in your neck, hoarseness, difficulty swallowing, or shortness of breath, inform your healthcare provider immediately, as these may be signs of thyroid cancer. 

Do Not Use Semaglutide If: 

– You or your family have a history of medullary thyroid carcinoma (MTC). – You or your family have been diagnosed with Multiple Endocrine Neoplasia syndrome type 2 (MEN 2). 

Use of Semaglutide: 

Semaglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist that can be used  for chronic weight management in combination with a reduced-calorie diet and increased physical activity for adults with: 

– A body mass index (BMI) of 30 kg/m² or greater (obesity), or

– A BMI of 27 kg/m² or greater (overweight) with at least one weight-related comorbid condition, such as hypertension, type 2 diabetes, or dyslipidemia. 

Limitations of Use: 

– Do not use Semaglutide in combination with other Semaglutide-containing products or GLP-1 receptor agonists. 

– The safety and efficacy of coadministration with other weight loss products have not been established. 

– Semaglutide has not been studied in patients with a history of pancreatitis. 

Who Should Not Use Semaglutide: 

– Individuals with a history or family history of MTC or MEN 2. 

– Those with a known allergy to Semaglutide. 

Administration Guidelines: 

Semaglutide is administered once a week per your provider, which can be injected into the stomach, thigh, with or without food. It’s crucial to follow your healthcare provider’s instructions regarding dosage adjustments and not alter or stop your treatment without consultation. 

Before Starting Semaglutide: 

Inform your healthcare provider of all medications you’re taking, including prescription drugs, over-the-counter medications, vitamins, and supplements, as there may be drug interactions. 

Particularly, watch out for: 

– DO NOT use Semaglutide with insulin or sulfonylureas. 

– Other GLP-1 medications. 

– Products used for weight loss, including dietary supplements. 

Special Considerations: 

Pregnancy: Do not use Semaglutide during pregnancy. If you are planning to become pregnant, discontinue use at least two months before. There may be risks to the unborn baby based on animal studies. 

Breastfeeding: Semaglutide has been detected in the milk of lactating rats. Consult your Excel Medical Medical Provider before use. 

Serious Side Effects to Monitor: 

If you experience a medical emergency, call 911 immediately. Be vigilant for the following serious side effects, particularly at the start of treatment or during dose changes:

Thyroid C-Cell Tumors: Watch for symptoms like a lump in your neck, hoarseness, trouble swallowing, or shortness of breath. 

Acute Pancreatitis: Seek immediate medical attention for severe abdominal pain that persists, with or without vomiting. 

Acute Gallbladder Disease: Report symptoms like upper stomach pain, yellowing of skin or eyes, fever, or clay-colored stools. 

Low Blood Sugar (Hypoglycemia): Monitor blood sugar levels closely, especially if you take other glucose-lowering medications. Symptoms may include dizziness, blurred vision, mood changes, sweating, or rapid heartbeat. 

Acute Kidney Injury: Stay hydrated to reduce the risk of dehydration, which can worsen kidney problems. 

Serious Allergic Reactions: Discontinue use immediately if you experience symptoms such as swelling of the face, lips, tongue, or throat, severe rash, or difficulty breathing. 

Diabetic Retinopathy: If you have type 2 diabetes, monitor any changes in vision. 

Increased Heart Rate: Report any episodes of a racing heartbeat while at rest. 

Suicidal Behavior and Ideation: Monitor mental health closely and report any sudden changes in mood, thoughts, or behavior. 

Common Side Effects: 

Common side effects include nausea, diarrhea, vomiting, constipation, abdominal pain, headache, fatigue, indigestion, dizziness, abdominal bloating, belching, low blood sugar (in patients with type 2 diabetes), gas, gastroenteritis, and acid reflux.

Reporting Side Effects:

You are encouraged to report negative side effects of prescription products:

– Contact Excel Medical at (833) 625-3392 (phone) or (833) 394-7744 (text).