Kate Wombwell
Article by: Kate Wombwell
Estimated 11 minutes read

Quick Summary: 

  • Omega-3s Are Essential Nutrients: These healthy fats play a key role in reducing inflammation, balancing hormones, and supporting brain and heart health.
  • They Help Regulate Hormones Naturally: Omega-3s support hormonal health by improving insulin sensitivity, lowering inflammation, and aiding in neurotransmitter function.
  • Omega-3 for Menopause Can Reduce Symptoms: Supplementing with omega-3s may ease hot flashes, boost mood, and support heart and brain health during menopause.
  • Omega-3 for PCOS Can Improve Hormonal Balance: Omega-3s can help manage PCOS symptoms by improving insulin response, lowering androgen levels, and supporting more regular cycles.
  • They Work Well With Other Natural Remedies: Omega-3s complement other hormone-balancing supplements and are a gentle, widely tolerated option for many women.
  • You Can Get Omega-3s From Food or Supplements: Fatty fish, seeds, and algae-based supplements are excellent sources, and choosing high-quality products is key.
  • They're Safe But Should Be Used Wisely: While generally safe, omega-3s can cause mild side effects and may interact with certain medications.
  • Real Women Have Seen Positive Results: Many women report improved mood, energy, and symptom relief when incorporating omega-3s into their wellness routine.
  • Consistency Makes Omega-3s More Effective: Daily use, alongside other healthy habits, can help support long-term hormonal balance and symptom relief.

Hormonal health can feel like a rollercoaster—especially when you're dealing with life-changing transitions like menopause or chronic conditions like polycystic ovary syndrome (PCOS). From mood swings to irregular periods to persistent fatigue, these hormonal shifts can disrupt nearly every aspect of your well-being.

More and more women are turning to nutrition-based solutions for support. And at the top of that list? Omega-3 fatty acids. These healthy fats have been shown to offer a wide range of benefits, from easing inflammation to helping regulate hormones.

In this article, we'll explore how omega-3s can support your body through menopause and PCOS, where to find them, how they work, and how to safely include them in your daily routine.

Fish oil pills and wooden cubes with inscription OMEGA 3 on light background

What Are Omega-3 Fatty Acids?

Omega-3 fatty acids are essential fats that your body can't make on its own—you have to get them through food or supplements. The three main types of omega-3s include:

  • ALA (alpha-linolenic acid): Found in plant-based sources like flaxseeds and walnuts.
  • EPA (eicosapentaenoic acid): Found primarily in fatty fish.
  • DHA (docosahexaenoic acid): Also found in fatty fish and essential for brain health.

These fats play important roles in regulating inflammation, supporting brain function, and maintaining heart health. They're also important in hormone production and signaling.

Believe it or not, most people don't consume enough omega-3s in their daily diet—especially EPA and DHA. For women dealing with menopause or PCOS, this can mean missing out on a powerful ally in managing symptoms naturally.

How Omega-3s Support Hormonal Health

Omega-3s have wide-reaching effects on hormone health, thanks in large part to their anti-inflammatory properties. Chronic inflammation is often a hidden driver of hormonal imbalances, and omega-3s can help reduce it at the cellular level.

Here's how omega-3s contribute to a healthier hormonal environment:

  • Insulin Sensitivity: Omega-3s improve how cells respond to insulin, which is vital for both PCOS management and reducing the risk of metabolic issues during menopause.
  • Neurotransmitter Support: DHA, in particular, supports brain health and helps regulate mood. This is key for managing anxiety and depression tied to hormonal fluctuations.
  • Hormone Production: Omega-3s assist in building healthy cell membranes, which are necessary for proper hormone receptor function.

This all adds up to a more balanced, resilient hormonal system, something both menopausal and PCOS-affected bodies desperately need.

Omega-3 For Menopause

Menopause marks the end of menstrual cycles and a significant drop in estrogen levels, which can lead to symptoms like hot flashes and night sweats, mood swings and irritability, fatigue and brain fog, and even increased risk of cardiovascular disease. 

Omega-3s can help smooth out the rough patches. Several studies suggest that omega-3 supplementation can reduce the frequency and severity of hot flashes (1). Other research has found benefits for mood and brain function. DHA and EPA help improve serotonin signaling, which can reduce the risk of depression—a common concern during perimenopause and postmenopause (2).

Finally, omega-3s support heart health by lowering triglyceride levels, reducing blood pressure, and improving vascular function—all crucial as estrogen's natural protective effects diminish.

These facts suggest that if you're navigating menopause and looking for a natural way to feel more like yourself, omega-3s are a smart and science-backed choice.

Omega-3 for PCOS

PCOS—known also as polycystic ovary syndrome— is a common but complex hormonal disorder that affects up to 1 in 10 women. Its root causes include insulin resistance, excess androgens (male hormones), and low-grade inflammation, all of which omega-3s can help address.

Omega-3s benefit women (3) with PCOS in a number of ways, including:

  • Improved Insulin Sensitivity: Omega-3s help your body use insulin more effectively, reducing insulin resistance and its associated symptoms, such as weight gain and irregular cycles.
  • Lower Inflammation: Chronic inflammation is a major contributor to PCOS symptoms. Omega-3s counter this by inhibiting inflammatory cytokines.
  • Hormonal Balance: Studies show that omega-3s can lower testosterone levels, helping to reduce acne, hair thinning, and unwanted hair growth.
  • Menstrual Regularity: By improving hormone signaling, omega-3s may help restore more predictable ovulation and cycles.
  • Fertility Support: Omega-3s have been linked to improved egg quality and reduced oxidative stress in the ovaries, offering support for women trying to conceive.

For women looking to manage PCOS without relying solely on medication, omega-3s may offer a gentle and effective path forward.

Comparing Omega-3s To Other Natural Supplements

There are plenty of natural supplements marketed to support hormonal health—each with its own unique benefits, so how do omega-3s compare?

Inositol vs. Omega-3s

Inositol, particularly myo-inositol and d-chiro-inositol, is widely recommended for women with PCOS, because it helps improve insulin sensitivity, promote more regular ovulation, and support egg quality (4). In fact, it's often referred to as a natural insulin-sensitizer. 

However, its effects can be amplified when paired with omega-3s. While inositol tackles insulin resistance and metabolic function, omega-3s reduce inflammation and support hormone balance. This makes them a powerful duo for managing PCOS symptoms holistically.

Evening Primrose Oil vs. Omega-3s

Evening primrose oil is best known for its ability to ease PMS-related breast tenderness, mood swings, and menstrual cramping. It contains gamma-linolenic acid (GLA), an omega-6 fatty acid that can have anti-inflammatory effects.

However, modern diets tend to be overly high in omega-6 fats and low in omega-3s, which can create a pro-inflammatory imbalance in the body. For that reason, supplementing with evening primrose oil may be more effective—and safer—when omega-3 intake is also optimized.

Vitamin D vs. Omega-3s

Vitamin D plays a big role in hormone production and regulation, immune function, and even mood. Deficiencies are common in women with both PCOS and menopause-related concerns.

Like omega-3s, vitamin D is a foundational supplement that supports overall health and is often recommended in tandem with omega-3s. Together, they enhance each other's effects—particularly when it comes to reducing inflammation, improving insulin function, and supporting mental well-being.

food sources of Omega 3 fatty acids

Why Omega-3s Stand Out

The biggest advantage of omega-3s is their versatility. While many supplements target one or two specific symptoms or systems, omega-3s provide wide-reaching benefits. They support brain function, cardiovascular health, hormonal balance, fertility, and even skin health—all with relatively few side effects and strong evidence to back them up.

Best Sources Of Omega-3s And Supplement Tips

You can get omega-3s from both food and supplements. Here are some great options:

Food Sources:

  • Fatty fish (especially salmon, mackerel, sardines, anchovies)
  • Chia seeds
  • Flaxseeds
  • Walnuts
  • Algal oil (for plant-based EPA and DHA)

Supplement Types:

  • Fish oil: The most common form; look for one that's high in EPA and DHA.
  • Krill oil: Contains phospholipids for better absorption and also includes antioxidants.
  • Algae oil: Ideal for vegetarians and vegans, this provides both EPA and DHA.

What to Look For:

  • At least 500-1,000 mg of combined EPA and DHA per serving
  • Third-party testing for purity and contaminants
  • Enteric coating to reduce aftertaste and improve absorption

For women managing menopause or PCOS, a typical daily dose of 1,000-2,000 mg of EPA and DHA combined is a good place to start. Still, always consult your healthcare provider before beginning a new supplement routine.

Are There Any Side Effects or Precautions?

Omega-3s are generally very safe, but it's still wise to understand potential side effects and precautions.

Possible Side Effects:

  • Mild digestive upset (nausea, bloating, or fishy burps)
  • Loose stools when taken in high doses
  • Fishy aftertaste (can be avoided with enteric-coated capsules)

Medication Interactions:

  • Omega-3s may thin the blood, so caution is advised for people taking anticoagulants or preparing for surgery.
  • Always check with your doctor if you're on medication for high blood pressure or diabetes.

If you're pregnant, breastfeeding, or managing a chronic illness, your provider can help tailor the right dose and form for your needs.

Making Omega-3s Part Of Your Hormonal Wellness Routine

If you're ready to try omega-3s, here are some simple ways to build them into your routine:

  • Add a fish oil or algae oil supplement to your breakfast.
  • Eat fatty fish twice a week—grilled salmon, sardine salad, or even canned mackerel on toast.
  • Sprinkle flax or chia seeds into smoothies, yogurt, or oatmeal.
  • Combine omega-3s with other hormone-friendly practices: balanced meals, regular exercise, and quality sleep.

To make it even easier, consider setting a reminder or keeping your supplement near your toothbrush or coffee maker. These are all small habits that help you stay on track. You can also prep meals in advance that include omega-3-rich ingredients, like baked salmon bowls or omega-3 trail mix with walnuts and pumpkin seeds.

Remember: the key to success is consistency. Unlike a quick-fix pill, omega-3s work gradually, building benefits over time. Stick with it, and you'll likely notice improvements in mood, energy, skin, and overall hormonal balance. Your body—and your hormones—will thank you for the steady support.

Final Thoughts

Menopause and PCOS can feel overwhelming, but the good news is that natural support is available, and omega-3s are one of the most powerful tools in your wellness toolkit.

From easing hot flashes and mood swings during menopause to improving insulin sensitivity and reducing inflammation in PCOS, omega-3s offer real, research-backed benefits. They're easy to incorporate, generally well-tolerated, and support your body in multiple ways.

Before starting any new supplement, it's wise to talk with a medical professional—especially if you have underlying conditions or take medications. But once you get the green light, adding omega-3s to your daily routine could be a small change that leads to big results.

Want help choosing the right omega-3s or building a complete hormone-support plan? Visit Fem Excel to get expert-backed support, tailored recommendations, and real answers for your hormonal health journey.

References:

(1) Mohamammy, M et al (2018). Effect of omega-3 supplements on vasomotor symptoms in menopausal women: A systematic review and meta-analysis. European Journal of Obstetrics & Gynecology and Reproductive Biology, 60, 112-121. https://doi.org/10.1016/j.jnutbio.2018.03.03https://www.sciencedirect.com/science/article/abs/pii/S030121151830335X#

(2) Grosso G, Galvano F, Marventano S, Malaguarnera M, Bucolo C, Drago F, Caraci F. Omega-3 fatty acids and depression: scientific evidence and biological mechanisms. Oxid Med Cell Longev. 2014;2014:313570. doi: 10.1155/2014/313570. Epub 2014 Mar 18. PMID: 24757497; PMCID: PMC3976923.

(3) Yang K, Zeng L, Bao T, Ge J. Effectiveness of Omega-3 fatty acid for polycystic ovary syndrome: a systematic review and meta-analysis. Reprod Biol Endocrinol. 2018 Mar 27;16(1):27. doi: 10.1186/s12958-018-0346-x. PMID: 29580250; PMCID: PMC5870911.

(4) Greff D, Juhász AE, Váncsa S, Váradi A, Sipos Z, Szinte J, Park S, Hegyi P, Nyirády P, Ács N, Várbíró S, Horváth EM. Inositol is an effective and safe treatment in polycystic ovary syndrome: a systematic review and meta-analysis of randomized controlled trials. Reprod Biol Endocrinol. 2023 Jan 26;21(1):10. doi: 10.1186/s12958-023-01055-z. PMID: 36703143; PMCID: PMC9878965.

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